Whole30 Paleo Mississippi Pot Roast

Category: Cozy, Hearty Recipes That Feel Like Home

This Whole30 and Paleo-friendly Mississippi pot roast features beef chuck slowly braised to tender perfection. Searing the meat locks in rich flavors before it simmers with beef broth, chives, garlic, onion, dill, and tangy pepperoncini peppers. Ghee is added for richness, creating a savory, melt-in-your-mouth main course. The pot roast is easy to prepare in a slow cooker and is perfect for serving over mashed potatoes, cauliflower, or rice. Leftovers store well, making it a great meal-prep option. Satisfying and wholesome, this dish brings comforting Southern-style flavors to your table.

A woman with a smile on her face.
Created By Melanie Carter
Updated on Sat, 23 Aug 2025 05:39:33 GMT
A plate of meat and potatoes. Pin
A plate of meat and potatoes. | mellierecipes.com

This healthy Mississippi Pot Roast is pure comfort food that fits both Whole30 and Paleo lifestyles. By swapping out traditional processed ingredients for cleaner pantry staples, it is deeply savory while using only real foods. The long slow cook transforms affordable chuck roast into melt-in-your-mouth bites surrounded by a tangy rich broth that is pure nostalgia for anyone who grew up with this pot roast on the Sunday table.

The first time I made this Paleo spin on Mississippi roast my husband thought I had ordered takeout it was that rich and satisfying. Now it is my answer when anyone in the house craves something hearty but I want to keep things healthy.

Ingredients

  • Beef chuck roast: Adds deep beefy flavor and becomes ultra tender after hours of braising Choose well-marbled meat for best results
  • Olive oil: Helps achieve a gorgeous sear on the roast Use extra virgin for flavor if you have it
  • Beef broth: Creates the flavorful braising liquid Choose low sodium with no additives for Whole30
  • Dried chives: Bring a gentle onion flavor and soft green flecks Dried are convenient but fresh can be used
  • Garlic powder: Adds robust flavor so the sauce tastes slow cooked from the start Use fresh garlic if preferred
  • Onion powder: Layers savory flavor and works well in sauces with long simmering
  • Dried dill: Lends a grassy brightness that makes every bite pop
  • Salt and black pepper: Essential for robustly seasoning every layer Go for kosher salt and freshly ground pepper if possible
  • Pepperoncini peppers and juice: Bring the signature zippy tang and mild heat that makes this roast addictive Look for crisp firm peppers in the jar
  • Ghee: Adds rich buttery flavor that melds into the sauce Clarified butter is traditional for Paleo but high quality butter can be substituted

Step-by-Step Instructions

Prepare the Roast:
Pat the chuck roast dry with paper towels then season it liberally with salt and pepper on all sides Let it sit to take the chill off while you prepare the skillet
Sear the Meat:
Heat olive oil in a large skillet over medium-high until hot and shimmering Add the roast and sear each side for about two minutes Turn only when there is a deep crust this step locks in savory flavor
Deglaze and Reduce:
After removing the roast pour in the beef broth and scrape up all those brown bits from the pan simmering to reduce the liquid by roughly half This will deepen the flavor of your finished sauce
Layer Into the Slow Cooker:
Set the seared roast in the slow cooker Pour the reduced broth over top then sprinkle with chives garlic powder onion powder dill salt and pepper Nestle the pepperoncini around the meat pour in the pepper brine and top everything with pats of ghee
Slow Cook Until Tender:
Cover and cook on low for eight to ten hours or high for five to six hours The roast is done when it is fork tender and shreds easily If it resists shredding cook it for another hour or two
Serve with Your Favorite Side:
Spoon the flavorful sauce and peppers over the thinly shredded beef Served best atop mashed potatoes cauliflower rice or polenta for a classic touch
A plate of food with meat and potatoes. Pin
A plate of food with meat and potatoes. | mellierecipes.com

I always look forward to the bright pop of flavor from the pepperoncini peppers in each bite They bring back memories of huge Sunday roasts at my grandma’s house where that tangy aroma filled the air as soon as you walked in

Storage Tips

Store leftovers in an airtight container in the fridge for four to five days The flavors get even better after a day and the meat remains juicy Simply reheat in a skillet with a splash of broth or in a microwave

Ingredient Substitutions

If you are out of ghee a high quality butter is perfectly tasty For a different twist try adding fresh herbs like thyme or parsley near the end of the cook For a less spicy finish use half the amount of pepperoncini or skip the extra juice

A white bowl filled with meat and potatoes. Pin
A white bowl filled with meat and potatoes. | mellierecipes.com

Serving Suggestions

I love piling this tender roast on top of creamy mashed potatoes or cauliflower for a grain free dinner Leftovers make amazing sandwiches lettuce wraps or even a topping for baked sweet potatoes

Cultural Context

Mississippi Pot Roast became a staple in Southern kitchens in the 1990s when resourceful home cooks found affordable cuts of beef could become mouthwatering with just a few pantry items This healthy update carries on that thrifty tradition but skips the processed mixes and keeps the spirit of down home comfort alive

Recipe FAQs

→ Can I use a different cut of beef?

Chuck roast is preferred for its tenderness, but brisket or shoulder roast can work if needed. Adjust cooking time for best results.

→ What can I serve with Mississippi pot roast?

It's delicious over mashed potatoes, cauliflower, polenta, or rice. Roasted vegetables or a fresh salad also pair well.

→ How do I store leftovers?

Keep leftovers in an airtight container in the fridge for up to 4-5 days or freeze for up to 3 months for easy reheating.

→ Is ghee necessary, or can I use another fat?

Ghee adds flavor and is Whole30/Paleo friendly, but butter or avocado oil can be substituted if dietary needs allow.

→ Can I make this in advance?

Absolutely! The flavors develop even more after resting a day. Reheat gently and serve as desired for convenience.

Whole30 Paleo Mississippi Pot Roast

Slow-cooked chuck roast with pepperoncini, herbs, and ghee delivers wholesome comfort with classic Mississippi flavor.

Prep Time
10 minutes
Cooking Duration
540 minutes
Overall Cooking Time
550 minutes
Created By: Melanie Carter

Recipe Category: Comfort Food Classics

Skill Level: Beginner-Friendly

Cuisine Style: American

Result Amount: 10 Portions

Diet Preferences: Low-Carb Friendly, Gluten-Free Option

What You’ll Need to Make This

→ Main

01 1.4–2.3 kg beef chuck roast
02 2 tablespoons olive oil
03 240 ml beef broth
04 1 tablespoon dried chives
05 2 teaspoons garlic powder
06 2 teaspoons onion powder
07 1 teaspoon dried dill
08 1 teaspoon salt
09 1 teaspoon freshly ground black pepper
10 6–8 whole pepperoncini peppers
11 1–2 tablespoons pepperoncini pepper juice
12 4 tablespoons ghee
13 Salt and pepper to taste

How to Prepare

Step 01

Remove beef chuck roast from refrigeration and its packaging. Pat dry thoroughly and season all sides generously with salt and pepper.

Step 02

Heat olive oil over medium-high to high heat in a large skillet. Once the oil shimmers, sear the seasoned beef on all sides for 1–2 minutes each until deeply golden brown.

Step 03

Place seared beef into the slow cooker. Deglaze the hot skillet with beef broth over medium-high heat, scraping browned bits from the pan. Allow to boil and reduce for 2–3 minutes until reduced by half.

Step 04

Pour the deglazed liquid over the beef in the slow cooker. Sprinkle the dried chives, garlic powder, onion powder, dried dill, salt, and pepper evenly over the roast. Arrange pepperoncini peppers around the meat and add pepperoncini pepper juice. Top with ghee distributed over the surface.

Step 05

Cover the slow cooker with a lid and cook on low for 8–10 hours or high for 5–6 hours, until the meat is fork tender.

Step 06

Check for tenderness; if necessary, cook for an additional 1–2 hours. Serve hot with your preferred accompaniment such as mashed potatoes, cauliflower mash, or polenta.

Extra Tips

  1. Leftovers keep refrigerated for up to 5 days or frozen for up to 3 months.

Tools Required

  • Slow cooker
  • Large skillet

Allergen Info

Review ingredients carefully for allergens. Reach out to your healthcare provider if you’ve got specific concerns.
  • Contains dairy if ghee is not clarified.

Nutritional Information (Per Serving)

Remember, this info is purely for reference and isn’t meant to replace dietary guidance.
  • Caloric Value: 328
  • Fat Content: 19.9 grams
  • Carbohydrate Content: 1.8 grams
  • Protein Content: 39 grams